Ann Atwater (July 1, 1935 – June 20, 2016) was an American civil rights activist in Durham, North Carolina. Throughout her career she helped improve the quality of life in Durham through programs such as Operation Breakthrough (Durham, North Carolina), a community organization dedicated to fight the War on Poverty. Her life and friendship with C.P. Ellis, a former member of the Ku Klux Klan, was the subject of a book, play, and feature film, The Best of Enemies.